Description

2-[2-(4,4'-Dimethoxytrityloxy)Ethylsulfonyl]Ethanol is a specialized, high-purity chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for the production of oligonucleotides and other complex biomolecules, where precise molecular architecture is critical. This compound is essential for research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in nucleic acid chemistry, drug discovery, and the synthesis of sophisticated molecular probes.

Application

• Oligonucleotide Synthesis: A crucial phosphoramidite precursor or modifier in solid-phase synthesis for research and therapeutic oligonucleotides.
• Antisense & siRNA Development: Used in the creation of chemically modified backbones to enhance stability and efficacy of gene-silencing agents.
• Molecular Biology Probes: Enables the synthesis of labeled nucleotides and probes for diagnostic assays and genomic research.
• Pharmaceutical Intermediates: Serves as a protected intermediate in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Facilitates the attachment of reporter molecules or functional groups to biomolecules via its reactive sulfonyl and hydroxyl termini.
• Academic & Industrial R&D: A valuable reagent for exploring new synthetic pathways in medicinal and bioorganic chemistry.

Basic Information

Product Name	2-[2-(4,4'-Dimethoxytrityloxy)Ethylsulfonyl]Ethanol
CAS No.	108783-01-3
Molecular Formula	C27H32O7S
Molecular Weight	500.61 g/mol
Synonyms	2-[2-(4,4'-Dimethoxytrityloxy)ethylsulfonyl]ethan-1-ol; DMT-Sulfone-Ethanol; 4,4'-Dimethoxytrityl Sulfone Ethanol; 2-{2-[(4,4'-Dimethoxytriphenylmethyl)oxy]ethylsulfonyl}ethanol; DMT-O-(CH2)2-SO2-(CH2)2-OH; DMT-sulfonylethanol; Oligonucleotide synthesis modifier; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-[2-(4,4'-Dimethoxytrityloxy)Ethylsulfonyl]Ethanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-process controls and final release testing protocols, with specifications designed to meet the exacting requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.