Description

3'-Amino-3'-Deoxy-5-Methyluridine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block for the synthesis of novel oligonucleotides and potential therapeutic agents, particularly in antiviral and anticancer drug discovery. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity intermediates for developing next-generation nucleic acid-based therapies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer drugs.
• Oligonucleotide Synthesis: Used as a modified building block for creating antisense oligonucleotides, siRNA, and aptamers with enhanced properties.
• Biochemical Research: Serves as a tool compound for studying enzyme mechanisms, particularly those involving thymidine kinase and other nucleoside-metabolizing enzymes.
• Probe Development: Utilized in the creation of labeled nucleosides for diagnostic assays and molecular imaging.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Item	Details
Product Name	3'-Amino-3'-Deoxy-5-Methyluridine
CAS No.	108630-07-5
Molecular Formula	C10H15N3O5
Molecular Weight	257.24 g/mol
Synonyms	5-Methyl-3'-amino-2',3'-dideoxyuridine; 3'-Amino-3'-deoxy-5-methyluridine; 3'-Amino-2',3'-dideoxy-5-methyluridine; 1-((2S,4R,5R)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 3'-Amino-5-methyl-2',3'-dideoxyuridine; 5-Methyld4T; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 3'-Amino-3'-Deoxy-5-Methyluridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.