Description

Bucyclovir Triphosphate CAS NO 108491-46-9 is a high-purity nucleotide analog triphosphate essential for biochemical and pharmaceutical research. This compound serves as a critical building block in the synthesis of nucleoside-based antiviral agents and as a substrate for enzymatic studies. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, molecular biology, and diagnostic assay development.

Application

• Antiviral Drug Research & Development: As a key intermediate in the synthesis of novel nucleoside analog prodrugs targeting viral polymerases.
• Biochemical Substrate: For enzymatic assays studying DNA/RNA polymerase activity, kinetics, and inhibition mechanisms.
• Molecular Biology Reagent: Used in in vitro transcription and primer extension experiments.
• Diagnostic Development: A component in the formulation of kits for detecting viral infections and related enzymatic activity.
• Pharmaceutical Intermediates: Serves as a high-value precursor in GMP manufacturing for active pharmaceutical ingredients (APIs).
• Academic Research: Fundamental studies on nucleotide metabolism, virology, and enzyme structure-function relationships.

Basic Information

Product Name	Bucyclovir Triphosphate
CAS No.	108491-46-9
Molecular Formula	C12H19N6O13P3
Molecular Weight	548.22 g/mol
Synonyms	Buciclovir triphosphate; 2-Amino-9-[(1,3-dihydroxy-2-propoxy)methyl]-1,9-dihydro-6H-purin-6-one 5'-(trihydrogen triphosphate); Bcv-TP; (R)-9-[4-Hydroxy-2-(hydroxymethyl)butyl]guanine triphosphate; Ganciclovir analog triphosphate; Nucleotide triphosphate analog; Antiviral nucleotide triphosphate
EINECS	Contact for details

Quality Control

Our Bucyclovir Triphosphate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥95.0%
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.