Description

5-Iodo-2-Methylbenzoyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive site for amide or ester formation while introducing iodine and methyl substituents for further functionalization or to modulate the properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders or as imaging agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a building block for creating complex organic molecules used in electronic displays and optoelectronic devices.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering material properties like solubility, thermal stability, or reactivity.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of specialized dyes and pigments where the iodine atom contributes to color properties and stability.

Basic Information

Product Name	5-Iodo-2-Methylbenzoyl Chloride
CAS No.	108440-70-6
Molecular Formula	C8H6ClIO
Molecular Weight	280.49 g/mol
Synonyms	2-Methyl-5-iodobenzoyl chloride; 5-Iodo-o-toluoyl chloride; 5-Iodo-2-methylbenzoic acid chloride; 2-Methyl-5-iodobenzoic acid chloride; (5-Iodo-2-methylphenyl)carbonyl chloride; 108440-70-6; 5-Iodo-2-methyl-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Methylbenzoyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to relevant industry standards and can support development projects requiring material for GLP or GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.