Description

Diethyl 4-Amino-4-Oxobutylphosphonate is a high-purity organophosphorus compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both phosphonate and amide functional groups, makes it a versatile intermediate for constructing complex molecules with tailored properties. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators with improved efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphonate-based ligands used in asymmetric catalysis and metal complexation.
• Material Science Research: Employed in the synthesis of functional polymers, flame retardants, and surface-modifying agents.
• Peptide Mimetics: The phosphonate moiety is utilized to create hydrolytically stable analogs of biologically active peptides.
• Chemical Biology Probes: Acts as a scaffold for developing activity-based probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	Diethyl 4-Amino-4-Oxobutylphosphonate
CAS No.	108371-74-0
Molecular Formula	C8H18NO4P
Molecular Weight	223.21 g/mol
Synonyms	4-Amino-4-oxobutylphosphonic Acid Diethyl Ester; Diethyl (4-Amino-4-oxobutyl)phosphonate; Butanamide, 4-(diethoxyphosphinyl)-; 4-(Diethoxyphosphinyl)butanamide; Phosphonic Acid, (4-Amino-4-oxobutyl)-, Diethyl Ester; AEBSF Phosphonate Analog (precursor); γ-Aminophosphonate Butyramide
EINECS	Contact for details

Quality Control

Our Diethyl 4-Amino-4-Oxobutylphosphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.