Description

Thymidylyl(3'>5')Thymidylyl(3'>5')-2'-*D Eoxycytidin is a specialized, high-purity dinucleotide analog used in advanced biochemical research and development. This compound is critical for studying nucleic acid interactions, enzyme mechanisms, and as a building block for synthetic oligonucleotides. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on molecular biology, diagnostics, and therapeutic discovery.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidite or solid-phase synthesis intermediate for creating modified DNA/RNA sequences.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies of polymerases, nucleases, and other nucleic acid-processing enzymes.
• Antisense & Therapeutic Development: Acts as a critical component in the development of antisense oligonucleotides and other nucleic acid-based therapeutics.
• Diagnostic Probe Development: Employed in the design and synthesis of labeled probes for hybridization assays and molecular diagnostics.
• Structural Biology Studies: Utilized in NMR and X-ray crystallography to investigate the structure and dynamics of nucleic acid complexes.
• Standards & Reference Materials: Provides a high-purity standard for analytical method development and quality control in oligonucleotide manufacturing.

Basic Information

Product Name	Thymidylyl(3'>5')Thymidylyl(3'>5')-2'-*D Eoxycytidin
CAS No.	108347-86-0
Molecular Formula	C25H31N6O15P2
Molecular Weight	717.51 g/mol
Synonyms	d(TpTp-2'-dC); Thymidylyl(3'-5')thymidylyl(3'-5')-2'-deoxycytidine; 2'-Deoxycytidylyl-(5'->3')-thymidylyl-(5'->3')-thymidine; TpTp-2'dC; Dinucleotide T-T-2'dC; 5'-O-[Hydroxy([hydroxy([(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl]oxy)phosphoryl]oxy)phosphoryl]thymidine
EINECS	Contact for details

Quality Control

Every batch of Thymidylyl(3'>5')Thymidylyl(3'>5')-2'-*D Eoxycytidin is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation by MS and NMR, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.