Description

Uridylyl(2'->5')Uridine Ammonium Salt is a specialized nucleotide derivative, a dimer of uridine linked via a unique 2'-5' phosphodiester bond. This compound is of significant interest in biochemical research for studying RNA structure, enzyme mechanisms, and oligonucleotide synthesis. It serves as a critical intermediate and reference standard for pharmaceutical and biotechnology companies focused on antiviral drug development, molecular diagnostics, and nucleic acid chemistry.

Application

• Biochemical Research: Used as a substrate or inhibitor for studying ribonucleases, RNA ligases, and other enzymes involved in RNA metabolism and editing.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel oligonucleotide-based therapeutics, including antisense and siRNA agents.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques within QC/QA laboratories.
• Antiviral Research: Investigated for its potential role in modulating immune response pathways, relevant to the development of treatments for viral infections.
• Diagnostic Probe Development: Utilized in the design and synthesis of specialized probes for detecting specific RNA sequences or structures.

Basic Information

Product Name	Uridylyl(2'->5')Uridine Ammonium Salt
CAS No.	108321-54-6
Molecular Formula	C18H26N6O13P • xNH3
Molecular Weight	Contact for details
Synonyms	2'-5'-UpU ammonium salt; Uridylyl(2'-5')uridine ammonium salt; P1,P2-Diuridine 2',5'-triphosphate ammonium salt; 2',5'-Linked uridine dinucleotide ammonium salt; 5'-O-Phosphonouridylyl-(2'->5')-uridine ammonium salt; Uridine 2',5'-bis(uridine 5'-phosphate) ammonium derivative; (2'->5')-UpU NH4+ salt
EINECS	Contact for details

Quality Control

Our Uridylyl(2'->5')Uridine Ammonium Salt is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards and can support development under cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.