Description

Cyclohexanecarbonyl Chloride, 5-Methyl-2-(1-Methylethyl)-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters because its specific stereochemistry and reactive acid chloride functional group make it a critical intermediate for constructing complex molecules with precise three-dimensional architecture. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, fragrances, and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is highly dependent on molecular configuration.
• Flavor & Fragrance Ingredient: Serves as a precursor for synthesizing specific terpene-based aroma compounds and musk analogs.
• Asymmetric Catalyst Ligand Preparation: Employed in the synthesis of complex, chiral ligands for transition metal catalysis.
• Material Science Research: A building block for creating novel polymers and liquid crystals with tailored stereochemical properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Item	Detail
Product Name	Cyclohexanecarbonyl Chloride, 5-Methyl-2-(1-Methylethyl)-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci)
CAS No.	108235-79-6
Molecular Formula	C11H19ClO
Molecular Weight	202.72 g/mol
Synonyms	(-)-Menthyl chloroformate; (1S,2R,5S)-2-Isopropyl-5-methylcyclohexanecarbonyl chloride; L-Menthyl chloroformate; (1S,2R,5S)-Menthyl chloroformate; (-)-Menthyl chlorocarbonate; (1S)-(-)-Menthyl chloroformate; L-Menthyl chlorocarbonate; (1S,2R,5S)-(-)-Menthyl chloroformate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonyl Chloride, 5-Methyl-2-(1-Methylethyl)-, [1S-(1Alpha,2Beta,5Alpha)]- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water; ensure containers are kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Keep away from strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.