Description

5-(2-Fluoroethyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl ]Pyrimidine-2,4-Dione CAS NO 108008-61-3 is a high-purity fluorinated nucleoside derivative, a key building block in advanced pharmaceutical research and development. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers a reliable and consistent starting material for complex molecular construction. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of potential therapeutic agents targeting viral polymerases and reverse transcriptases.
• Oncology Research: Serves as a building block for creating nucleoside-based chemotherapeutic candidates.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Radiopharmaceuticals: Potential use as a precursor for 18F-labeled compounds in Positron Emission Tomography (PET) imaging.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies to optimize drug potency and selectivity.

Basic Information

Product Name	5-(2-Fluoroethyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl ]Pyrimidine-2,4-Dione
CAS No.	108008-61-3
Molecular Formula	C11H15FN2O6
Molecular Weight	290.25 g/mol
Synonyms	5-(2-Fluoroethyl)-2'-deoxyuridine; 5-(2-Fluoroethyl)deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-(2-fluoroethyl)pyrimidine-2,4(1H,3H)-dione; 5-(2-Fluoroethyl)-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione; FEdU; 5-Fluoroethyldeoxyuridine
EINECS	Contact for details

Quality Control

Our 5-(2-Fluoroethyl)-1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl ]Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports research requiring high-purity reference standards and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.