Description

4-Acetyloxy-2,2-Dimethylbutyrylchloride is a specialized acid chloride derivative, a key reactive intermediate in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 4-acetyloxy-2,2-dimethylbutyryl moiety, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring sterically hindered ester or amide functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its specific acyl group imparts desired biological activity.
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with tailored properties such as specific degradation profiles or side-chain functionalities.
• Fine Chemical Production: Employed in the multistep synthesis of complex fragrance compounds, dyes, and other high-value specialty chemicals.
• Peptide & Protein Modification: Acts as an acylating agent for modifying amino acid side chains or terminal groups in peptide research and bioconjugation.
• Material Science Research: Utilized in surface functionalization and the development of novel organic-inorganic hybrid materials.

Basic Information

Item	Details
Product Name	4-Acetyloxy-2,2-Dimethylbutyrylchloride
CAS No.	107998-33-4
Molecular Formula	C8H13ClO3
Molecular Weight	192.64 g/mol
Synonyms	4-(Acetyloxy)-2,2-dimethylbutanoyl chloride; 2,2-Dimethyl-4-acetoxybutyryl chloride; 4-Acetoxy-2,2-dimethylbutyryl chloride; 4-Acetyloxy-2,2-dimethylbutanoic acid chloride; 2,2-Dimethyl-4-acetyloxybutyryl chloride; 4-(Acetyloxy)-2,2-dimethylbutyryl chloride; Butanoyl chloride, 4-(acetyloxy)-2,2-dimethyl-
EINECS	Contact for details

Quality Control

Our 4-Acetyloxy-2,2-Dimethylbutyrylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.