Description

Nucleoside Oq CAS NO 107865-20-3 is a high-purity, modified nucleoside building block essential for advanced oligonucleotide synthesis. This compound is critical for researchers and manufacturers developing next-generation therapeutic and diagnostic agents, where precise molecular structure and purity are paramount. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for applications including antisense oligonucleotides, siRNA, and aptamer development.

Application

• Pharmaceutical Intermediate: A key raw material in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Oligonucleotide Synthesis: Serves as a protected phosphoramidite monomer for solid-phase synthesis of DNA/RNA sequences.
• Antisense Therapy Development: Used in the research and production of antisense oligonucleotides (ASOs) for targeted gene silencing.
• siRNA and miRNA Constructs: Integral component in creating small interfering RNA (siRNA) and microRNA (miRNA) for RNA interference applications.
• Diagnostic Probe Synthesis: Employed in manufacturing labeled probes for genetic testing and molecular diagnostics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis.
• Aptamer Development: Building block for the combinatorial synthesis of nucleic acid aptamers used in biosensing and therapeutics.

Basic Information

Item	Details
Product Name	Nucleoside Oq
CAS No.	107865-20-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Oq Nucleoside; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-oxoquinazoline; 4-Oxo-1-(2-deoxy-β-D-ribofuranosyl)quinazoline; 2'-Deoxy-4-oxoquinazoline riboside; dOq; Deoxyoxoquinazoline nucleoside
EINECS	Contact for details

Quality Control

Our Nucleoside Oq is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.