Description

2-Thiopheneacetyl Chloride, 5-Cyano-α-Oxo- (9Ci) is a high-purity, reactive organic intermediate characterized by its functionalized thiophene backbone. This compound is critical for advanced chemical synthesis, offering a versatile building block for constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the thiophene moiety can contribute to biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of novel conductive polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-Thiopheneacetyl Chloride, 5-Cyano-α-Oxo- (9Ci)
CAS No.	107748-17-4
Molecular Formula	C8H4ClNO2S
Molecular Weight	213.64 g/mol
Synonyms	5-Cyano-2-thiopheneacetyl chloride, α-oxo-; 5-Cyano-2-thiopheneglyoxyl chloride; 2-(5-Cyanothiophen-2-yl)-2-oxoacetyl chloride; 5-Cyanothiophene-2-glyoxylic acid chloride; Oxo(5-cyanothiophen-2-yl)acetyl chloride; (5-Cyanothiophen-2-yl)(oxo)acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetyl Chloride, 5-Cyano-α-Oxo- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory documentation packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.