Description

2-Thiopheneacetyl Chloride, 3,4-Dimethyl-α-Oxo- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group on a substituted thiophene scaffold. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for chemists and R&D teams in the agrochemical, pharmaceutical, and material science industries seeking to introduce the unique 3,4-dimethylthiophene moiety into target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological or metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene ring.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers and conductive materials.
• Ligand and Catalyst Development: Employed to construct complex ligands for metal-organic frameworks (MOFs) or asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design of molecular probes and diagnostic agents for biochemical research.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up production in fine chemical facilities.

Basic Information

Item	Detail
Product Name	2-Thiopheneacetyl Chloride, 3,4-Dimethyl-α-Oxo- (9Ci)
CAS No.	107748-11-8
Molecular Formula	C9H9ClO2S
Molecular Weight	216.68 g/mol
Synonyms	3,4-Dimethyl-2-thiopheneacetyl chloride; 3,4-Dimethyl-2-thiopheneglyoxylic acid chloride; 2-(3,4-Dimethyl-2-thienyl)-2-oxoacetyl chloride; 3,4-Dimethyl-2-thienylglyoxyloyl chloride; 2-(3,4-Dimethylthiophen-2-yl)-2-oxoacetyl chloride; α-Oxo-3,4-dimethyl-2-thiopheneacetyl chloride; (3,4-Dimethyl-2-thienyl)(oxo)acetyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetyl Chloride, 3,4-Dimethyl-α-Oxo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Light yellow to amber liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.