Description

2-Thiopheneacetyl Chloride, 5-Fluoro-α-Oxo- (9Ci) is a high-purity, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive acid chloride group and unique thiophene-fluorine scaffold, enabling precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to construct novel, fluorinated active ingredients for crop protection products, enhancing their metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalization agent for developing specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and ligands for studying biological targets and mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis services, supporting R&D projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	2-Thiopheneacetyl Chloride, 5-Fluoro-α-Oxo- (9Ci)
CAS No.	107748-10-7
Molecular Formula	C7H4ClFO2S
Molecular Weight	206.62 g/mol
Synonyms	5-Fluoro-2-thiopheneacetyl chloride, α-oxo-; 5-Fluoro-2-thiopheneglyoxylic acid chloride; 2-(5-Fluorothiophen-2-yl)-2-oxoacetyl chloride; 5-Fluoro-2-thienylglyoxyloyl chloride; (5-Fluorothiophen-2-yl)(oxo)acetyl chloride; 5-Fluoro-α-oxo-2-thiopheneacetyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Thiopheneacetyl Chloride, 5-Fluoro-α-Oxo- (9Ci) is produced and tested under strict quality management protocols. We ensure compliance with relevant industry standards for research and development chemicals. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reproducible results and supply chain reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, open flames, and incompatible materials such as bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.