Description

2-Thiopheneacetyl Chloride, 3-Chloro-α-Oxo- (9Ci) is a specialized organic building block featuring a reactive acid chloride group on a substituted thiophene scaffold. This compound matters as a critical intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique structure enables the introduction of key functional groups. It is primarily needed by research chemists and process development scientists in fine chemical synthesis, medicinal chemistry, and material science research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or precursor for conducting polymers and advanced organic electronic materials.
• Peptide Mimetics & Bioconjugation: The reactive acid chloride group is utilized for amide bond formation in creating peptide analogs or for labeling biomolecules.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Thiopheneacetyl Chloride, 3-Chloro-α-Oxo- (9Ci)
CAS No.	107748-09-4
Molecular Formula	C7H4Cl2OS
Molecular Weight	207.08 g/mol
Synonyms	3-Chloro-2-thiopheneglyoxyl Chloride; 3-Chloro-2-thienylglyoxylic Acid Chloride; 3-Chloro-2-thiopheneacetyl Chloride; 2-Thiopheneacetyl Chloride, 3-Chloro-α-oxo-; (3-Chloro-2-thienyl)(oxo)acetyl Chloride; α-Oxo-3-chloro-2-thiopheneacetyl Chloride; 3-Chloro-2-thienylglyoxalyl Chloride
EINECS	Contact for details

Quality Control

Our 2-Thiopheneacetyl Chloride, 3-Chloro-α-Oxo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Light yellow to brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.