Description

2,6-Diaminopurine 2',3'-Dideoxyriboside is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a key synthetic intermediate and building block for the creation of novel antiviral and anticancer agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of nucleoside-based therapeutics, particularly those targeting viral polymerases and DNA replication processes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral drugs.
• Antiviral Research: Used in the development of experimental compounds targeting viruses such as HIV, HBV, and HCV.
• Oncology Research: Serves as a building block for creating nucleoside analogs that inhibit cancer cell proliferation.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate polymerase mechanisms.
• Prodrug Development: Utilized in the design and synthesis of prodrugs to enhance the bioavailability of active nucleoside agents.
• Chemical Biology: Acts as a molecular tool for probing nucleic acid metabolism and related biological pathways.

Basic Information

Product Name	2,6-Diaminopurine 2',3'-Dideoxyriboside
CAS No.	107550-73-2
Molecular Formula	C11H15N5O3
Molecular Weight	265.27 g/mol
Synonyms	2',3'-Dideoxy-2,6-diaminopurine riboside; 2,6-Diamino-9-(2,3-dideoxy-β-D-erythro-pentofuranosyl)purine; 2,6-DAP-ddR; DAP-ddR; 2,6-Diaminopurine dideoxyriboside; 9-[(2R,5S)-5-(Hydroxymethyl)oxolan-2-yl]-2,6-diaminopurin-1-ium
EINECS	Contact for details

Quality Control

Our 2,6-Diaminopurine 2',3'-Dideoxyriboside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.