Description

2,3,5,6-Tetrafluorobenzoyl Chloride is a highly reactive fluorinated aromatic acid chloride derivative, serving as a critical building block for introducing the tetrafluorobenzoyl moiety into target molecules. Its value lies in enabling the synthesis of advanced materials and active compounds with enhanced properties such as thermal stability, chemical resistance, and specific biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where precise fluorination is required for product development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs requiring fluorinated aromatic structures to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, enhancing their dielectric anisotropy and overall performance.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, resulting in materials with superior oil and water repellency, and chemical resistance for coatings and high-performance plastics.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic substitution reactions in complex organic molecule construction within R&D settings.
• Dye & Pigment Manufacturing: Used in the production of specialized fluorinated dyes and pigments that offer unique color fastness and stability properties.

Basic Information

Product Name	2,3,5,6-Tetrafluorobenzoyl Chloride
CAS No.	107535-73-9
Molecular Formula	C7HF4ClO
Molecular Weight	212.53 g/mol
Synonyms	2,3,5,6-Tetrafluorobenzoyl chloride; Perfluorobenzoyl Chloride (ambiguous, but common); Benzoyl chloride, 2,3,5,6-tetrafluoro-; Tetrafluorobenzoyl chloride; 2,3,5,6-Tetrafluorobenzoic acid chloride; TFBC; TFBzCl
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluorobenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.