Description

5-Ribofuranosylnicotinamide is a specialized nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a key intermediate and building block in the synthesis of novel nucleotide derivatives and enzyme cofactors. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in drug discovery, enzymology, and metabolic pathway studies.

Application

• Biochemical Research: Used as a precursor in the study of NAD(P)+ biosynthesis and related metabolic pathways.
• Pharmaceutical Intermediates: Serves as a critical building block for the synthesis of novel nucleoside-based drug candidates and prodrugs.
• Enzyme Substrate Studies: Employed in enzymatic assays to investigate the activity and kinetics of specific transferases and synthetases.
• Cofactor Analog Synthesis: A starting material for creating modified nicotinamide adenine dinucleotide (NAD) analogs for mechanistic studies.
• Academic & Industrial R&D: Essential for fundamental research in universities, contract research organizations (CROs), and biotech companies.

Basic Information

Product Name	5-Ribofuranosylnicotinamide
CAS No.	107325-67-7
Molecular Formula	C11H14N2O6
Molecular Weight	270.24 g/mol
Synonyms	Nicotinamide Riboside (NR); 1-(β-D-Ribofuranosyl)-3-carbamoylpyridinium; 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium; Nicotinamide Ribonucleoside; Nicotinamide Riboside Chloride precursor; N-Ribosylnicotinamide; 1,4-Dihydronicotinamide riboside analog; 5-Ribosylnicotinamide
EINECS	Contact for details

Quality Control

Our 5-Ribofuranosylnicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade research standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.