Description

Cholestane-3,7,26,27-Tetrol is a high-purity sterol derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical reference standard and synthetic intermediate for studying cholesterol metabolism, bile acid biosynthesis, and related metabolic pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors requiring precise molecular tools for analytical method development and process validation.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative analysis of sterols and related metabolites in drug development and quality control.
• Biochemical Research: A key intermediate in the study of cholesterol catabolism and the enzymatic pathways involved in bile acid formation.
• Metabolite Synthesis: Serves as a precursor for the synthesis of more complex steroidal compounds and labeled analogs for tracer studies.
• Diagnostic Reagent Manufacturing: Employed in the production of calibrators and controls for clinical diagnostic assays targeting lipid disorders.
• Academic Research: Utilized in universities and research institutes for fundamental studies on lipid biochemistry and cell membrane biology.

Basic Information

Product Name	Cholestane-3,7,26,27-Tetrol
CAS No.	107088-80-2
Molecular Formula	C27H48O4
Molecular Weight	436.67 g/mol
Synonyms	3α,7α,26,27-Tetrahydroxycholestane; (25R)-3α,7α,26,27-Tetrahydroxy-5β-cholestane; 5β-Cholestane-3α,7α,26,27-tetrol; Cholestanetetrol; Tetrahydroxycholestane
EINECS	Contact for details

Quality Control

Our Cholestane-3,7,26,27-Tetrol is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.