Description

5-Aza-2'-Deoxy-6-Oxo Cytidine is a chemically modified nucleoside analog of deoxycytidine, designed for advanced biochemical and pharmaceutical research. This compound is valued for its role as a potent epigenetic modulator, specifically targeting DNA methyltransferase activity. It is primarily utilized by researchers and developers in the fields of oncology, epigenetics, and medicinal chemistry for investigating DNA methylation patterns and developing novel therapeutic agents.

Application

• Epigenetic Research: Used as a biochemical tool to study DNA methylation and demethylation processes in cellular models.
• Oncology Research: Investigated for its potential as a hypomethylating agent in cancer cell line studies and preclinical drug development.
• Pharmaceutical Intermediates: Serves as a key synthetic intermediate or reference standard in the development of novel nucleoside-based therapeutics.
• Biochemical Assays: Employed in enzymatic assays to study the inhibition and mechanism of action of DNA methyltransferases (DNMTs).
• Academic Research: Utilized in university and institutional labs for fundamental research in genetics, cell biology, and chemical biology.

Basic Information

Product Name	5-Aza-2'-Deoxy-6-Oxo Cytidine
CAS No.	106966-55-6
Molecular Formula	C8H11N5O5
Molecular Weight	257.21 g/mol
Synonyms	6-Oxo-5-aza-2'-deoxycytidine; 5-Aza-2'-deoxycytidin-6-one; 5-Aza-dC-6-one; 2'-Deoxy-5-azacytidin-6-one; NSC 777715; 5-Aza-2'-deoxy-6-oxocytidine; 6-Oxo-decitabine; 4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting traceability and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.