Description

[6As,(-)]-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole-8β-Ol is a complex, high-purity organic compound featuring a unique isothiocyanate functional group attached to a fused polycyclic indole structure. This compound matters as a valuable synthetic intermediate and a key building block for advanced chemical synthesis, particularly in the development of novel pharmacologically active molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies due to its reactive isothiocyanate group, which allows for conjugation and derivatization.
• Bioconjugation Chemistry: The isothiocyanate moiety enables covalent bonding with amines, making it useful for labeling proteins, antibodies, or other biomolecules in research settings.
• Organic Synthesis Building Block: Employed in advanced organic synthesis to construct complex, polycyclic molecular architectures found in natural products and specialty chemicals.
• Chemical Biology Probes: Acts as a starting material for developing activity-based probes used to study enzyme function and mechanism in biological systems.

Basic Information

Product Name	[6As,(-)]-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole-8β-Ol
CAS No.	106865-66-1
Molecular Formula	C22H26N2OS
Molecular Weight	366.52 g/mol
Synonyms	(-)-9α-Ethenyl-10α-isothiocyanato-6,6,9-trimethyl-2,3,4,6,6a,7,8,9,10,10a-decahydronaphtho[1,2,3-cd]indol-8β-ol; 9α-Ethenyl-10α-isothiocyanato-6,6,9-trimethyl-2,3,4,6,6a,7,8,9,10,10a-decahydronaphtho[1,2,3-cd]indol-8β-ol; NSC 339579; Complex Indole Isothiocyanate Derivative; Polycyclic Indole Isothiocyanate
EINECS	Contact for details

Quality Control

Our [6As,(-)]-9α-Ethenyl-2,6,6Aα,7,8,9,10,10Aα-Octahydro-10α-Isothiocyanato-6,6,9-Trimethylnaphtho[1,2,3-Cd]Indole-8β-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.