Description

Lactosyl Isothiocyanate CAS NO 106848-83-3 is a specialized glycosyl isothiocyanate derivative, a crucial bifunctional reagent that combines the structural features of lactose with a highly reactive isothiocyanate group. This compound is primarily valued for its role as a key intermediate in the synthesis of glycoconjugates and targeted probes for biomedical research. It is essential for researchers and manufacturers in the fields of glycobiology, pharmaceutical development, and diagnostic reagent production, where precise carbohydrate-protein conjugation is required.

Application

• Glycoconjugate Synthesis: A vital building block for creating neoglycoconjugates, glycoproteins, and glycolipids for research and therapeutic applications.
• Bioconjugation and Labeling: Used to covalently attach lactose moieties to proteins, peptides, antibodies, or surfaces via its reactive isothiocyanate group, enabling targeted delivery or imaging.
• Lectinology and Carbohydrate-Binding Studies: Serves as a precursor for probes to study lectin-carbohydrate interactions, which are fundamental in immunology and cell signaling.
• Diagnostic Reagent Development: Employed in the manufacturing of reagents for diagnostic assays that detect specific carbohydrate-binding proteins or pathogens.
• Drug Delivery Systems: Facilitates the development of targeted drug delivery vehicles by conjugating therapeutic agents to lactose-based carriers for hepatocyte-specific uptake.
• Biomaterial Functionalization: Used to modify surfaces of polymers or nanoparticles with lactose residues to enhance biocompatibility or create bioactive materials.

Basic Information

Item	Details
Product Name	Lactosyl Isothiocyanate
CAS No.	106848-83-3
Molecular Formula	C15H25NO11S
Molecular Weight	427.43 g/mol
Synonyms	4-Isothiocyanatophenyl β-lactoside; β-Lactosyl phenylisothiocyanate; Lactose phenylisothiocyanate; p-Isothiocyanatophenyl β-D-lactopyranoside; Lactosyl phenyl isothiocyanate; PITC-Lactose; 1-Thio-β-D-lactosyl isothiocyanate (theoretical); Lactose-based isothiocyanate reagent
EINECS	Contact for details

Quality Control

Our Lactosyl Isothiocyanate is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and bioconjugation applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere after opening and allowed to equilibrate to room temperature before use to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.