Description

1,3-Dithiolane-2-Carbonyl Chloride, 4-Methyl-, trans- (9Ci) is a specialized organosulfur building block featuring a reactive acid chloride group and a protected dithiolane moiety. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, ligands, and functional materials where the introduction of a sulfur-containing heterocycle is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting metabolic or neurological pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that leverage sulfur chemistry for enhanced activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating chiral dithiolane-based ligands used in asymmetric catalysis.
• Material Science Research: Employed in the development of organic electronic materials and polymers with unique optoelectronic properties.
• Chemical Biology Probes: Useful for synthesizing probes that study protein function or cellular processes involving thiol/disulfide exchange.

Basic Information

Product Name	1,3-Dithiolane-2-Carbonyl Chloride, 4-Methyl-, trans- (9Ci)
CAS No.	106744-89-2
Molecular Formula	C5H7ClOS2
Molecular Weight	182.69 g/mol
Synonyms	trans-4-Methyl-1,3-dithiolane-2-carbonyl chloride; (4R,5R)-4-Methyl-1,3-dithiolane-2-carbonyl chloride; (4S,5S)-4-Methyl-1,3-dithiolane-2-carbonyl chloride; 4-Methyl-1,3-dithiolane-2-carbonyl chloride, trans-; 1,3-Dithiolane-2-carbonyl chloride, 4-methyl-, trans-; 2-(Chlorocarbonyl)-4-methyl-1,3-dithiolane; 4-Methyl-1,3-dithiolane-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1,3-Dithiolane-2-Carbonyl Chloride, 4-Methyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.