Description

1,3-Dithiolane-2-Carbonylchloride,4,5-Dimethyl-,(2Alpha,4Alpha,5Beta)-(9Ci) is a specialized chiral building block and reactive intermediate of significant interest in advanced organic synthesis. Its value lies in its unique dithiolane-protected carbonyl chloride functionality, which enables the controlled introduction of complex molecular fragments. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• As a key chiral synthon in the asymmetric synthesis of complex natural products and pharmaceutical candidates.
• Utilized in the preparation of thioketal-protected intermediates for multi-step organic transformations.
• Acts as a versatile acylating agent in the synthesis of amides, esters, and other carbonyl derivatives under mild conditions.
• Employed in medicinal chemistry research for constructing sulfur-containing heterocycles and probing structure-activity relationships.
• Serves as a precursor in the development of ligands for catalysis and functional materials.
• Used in process chemistry for scaling up the production of target molecules requiring this specific stereochemistry.

Basic Information

Product Name	1,3-Dithiolane-2-Carbonylchloride,4,5-Dimethyl-,(2Alpha,4Alpha,5Beta)-(9Ci)
CAS No.	106723-96-0
Molecular Formula	C6H9ClOS2
Molecular Weight	196.72 g/mol
Synonyms	(2R,4R,5S)-4,5-Dimethyl-1,3-dithiolane-2-carbonyl chloride; (2α,4α,5β)-4,5-Dimethyl-1,3-dithiolane-2-carbonyl chloride; 4,5-Dimethyl-1,3-dithiolane-2-carbonyl chloride, (2α,4α,5β)-; (2R,4R,5S)-4,5-Dimethyl-[1,3]dithiolane-2-carbonyl chloride; 1,3-Dithiolane-2-carbonyl chloride, 4,5-dimethyl-, (2α,4α,5β)-; 106723-96-0; (2R,4R,5S)-4,5-dimethyl-1,3-dithiolane-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1,3-Dithiolane-2-Carbonylchloride,4,5-Dimethyl-,(2Alpha,4Alpha,5Beta)-(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral purity verification and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and specific test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.