Description

3'-5'-Di-o-Acetyl-2'-Deoxyinosine is a key nucleoside derivative and a protected intermediate used in the synthesis of modified oligonucleotides. This compound is critical for researchers and manufacturers developing novel therapeutic agents and diagnostic tools that target genetic pathways. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for applications in antiviral and anticancer drug discovery, as well as in molecular biology research.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of nucleoside analog prodrugs and antiviral/anticancer agents.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase or solution-phase synthesis of modified DNA and RNA strands.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and DNA repair mechanisms.
• Prodrug Development: The acetyl groups can be cleaved in vivo, making it a valuable precursor for designing prodrugs with improved bioavailability.
• Antiviral Drug Research: Particularly relevant in the development of compounds targeting viral polymerases and reverse transcriptases.
• Labeled Compound Synthesis: A starting material for the preparation of isotopically labeled (e.g., 13C, 15N) nucleosides for metabolic tracing studies.

Basic Information

Product Name	3'-5'-Di-o-Acetyl-2'-Deoxyinosine
CAS No.	106568-79-0
Molecular Formula	C14H16N4O6
Molecular Weight	336.30 g/mol
Synonyms	2'-Deoxyinosine 3',5'-diacetate; 9-[(2R,4S,5R)-4-Acetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one; 3',5'-Di-O-acetyl-2'-deoxyinosine; 2'-Deoxy-3',5'-di-O-acetyl-inosine; 2'-dIno-3',5'-diAc; N6-Hydroxy-2'-deoxyadenosine 3',5'-diacetate (related form)
EINECS	Contact for details

Quality Control

Our 3'-5'-Di-o-Acetyl-2'-Deoxyinosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We can support development projects requiring compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.