Description

Methyl 2,2,3,4,4,4-Hexafluorobutyrate is a high-purity fluorinated ester building block, valued for its unique reactivity profile and ability to introduce fluorine atoms into target molecules. This compound is essential for synthetic chemists developing advanced materials and active ingredients where fluorination is a key design strategy. It is primarily utilized in the research and production of pharmaceuticals, agrochemicals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging fluorine's ability to modulate metabolic stability, bioavailability, and lipophilicity.
• Agrochemical Synthesis: Used in creating novel fluorinated herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Fluorinated Polymer & Material Science: Serves as a monomer or modifier in the production of specialty polymers, coatings, and surfactants with enhanced oil/water repellency, chemical resistance, and thermal stability.
• Organic Synthesis Building Block: Employed in nucleophilic substitution, hydrolysis, and transesterification reactions to introduce the 2,2,3,4,4,4-hexafluorobutyl moiety into complex organic frameworks.
• Liquid Crystal & Electronic Materials: A potential precursor for fluorinated components in liquid crystal displays (LCDs) and dielectric fluids, contributing to improved performance characteristics.

Basic Information

Product Name	Methyl 2,2,3,4,4,4-Hexafluorobutyrate
CAS No.	106538-78-7
Molecular Formula	C5H4F6O2
Molecular Weight	210.08 g/mol
Synonyms	Methyl hexafluorobutyrate; 2,2,3,4,4,4-Hexafluorobutyric acid methyl ester; Methyl perfluorobutyrate; Methyl 4,4,4-trifluoro-3-(trifluoromethyl)butyrate; Methyl α,β,β-trifluoro-γ,γ,γ-trifluorobutyrate; MFB; Methyl 2,2,3,4,4,4-hexafluorobutanoate
EINECS	Contact for details

Quality Control

Our Methyl 2,2,3,4,4,4-Hexafluorobutyrate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.320 - 1.340
Density (20°C)	1.45 - 1.55 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.