Description

3-Fluoro-2-Methoxybenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the 3-fluoro-2-methoxybenzoyl moiety. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated benzoyl structure.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Material Science: Employed in the preparation of specialized ligands for catalysis and as a monomer or modifier for advanced polymeric materials.
• Custom Synthesis & Contract Research: An essential reagent for custom synthesis houses and CROs (Contract Research Organizations) working on client-specific fluorinated compounds.
• Chemical Research: Utilized in academic and industrial labs for methodological development and exploring new chemical spaces in fluoroorganic chemistry.

Basic Information

Product Name	3-Fluoro-2-Methoxybenzoyl Chloride
CAS No.	106428-06-2
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	3-Fluoro-2-methoxybenzoic acid chloride; 2-Methoxy-3-fluorobenzoic acid chloride; 3-Fluoro-o-anisoyl chloride; 2-Methoxy-3-fluorobenzoyl chloride; Benzoic acid, 3-fluoro-2-methoxy-, chloride; 106428-06-2 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methoxybenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards where required, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from moisture, heat, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.