Description

1,3-Dioxolane-4-Carbonyl Chloride, 2,2-Dimethyl-4-(2-Propenyl)-, (S)- (9Ci) is a high-purity, chiral acyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce a protected carbonyl function with a defined stereocenter, enabling the construction of complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, antifungal, and cardiovascular drug research.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is enantiomer-dependent.
• Peptide Mimetics & Prodrug Development: Employed to create ester or amide linkages in the design of peptide analogs and prodrug formulations to enhance bioavailability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands and organocatalysts.
• Fine Chemical & Specialty Material Production: Integral to the multistep synthesis of complex fragrances, flavors, and specialty polymers requiring specific stereochemistry.

Basic Information

Product Name	1,3-Dioxolane-4-Carbonyl Chloride, 2,2-Dimethyl-4-(2-Propenyl)-, (S)- (9Ci)
CAS No.	106268-01-3
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	(S)-2,2-Dimethyl-4-(2-propenyl)-1,3-dioxolane-4-carbonyl chloride; (4S)-2,2-Dimethyl-4-(prop-2-en-1-yl)-1,3-dioxolane-4-carbonyl chloride; (S)-4-Allyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl chloride; (S)-(-)-4-Allyl-2,2-dimethyl-1,3-dioxolane-4-carbonyl chloride; Chiral Dioxolane Carbonyl Chloride; Allyl Dioxolane Carbonyl Chloride, (S)-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane-4-Carbonyl Chloride, 2,2-Dimethyl-4-(2-Propenyl)-, (S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and maintain product integrity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.