Description

6-Iodo-Uridine is a halogenated nucleoside analog, a crucial building block in organic synthesis and biochemical research. This compound is valued for its role as a versatile intermediate in the development of antiviral and anticancer agents, as well as in oligonucleotide synthesis. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and diagnostic reagents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a modified nucleoside in studies of nucleic acid structure, function, and enzyme mechanisms.
• Oligonucleotide Synthesis: Serves as a modified building block for introducing iodine labels or functional groups into DNA/RNA strands for probes and diagnostics.
• Radiopharmaceuticals: Potential precursor for the development of iodine-labeled compounds for medical imaging (e.g., SPECT).
• Chemical Biology: Tool compound for cross-linking studies and investigating protein-nucleic acid interactions.
• Fine Chemical Synthesis: Intermediate for creating more complex, functionalized organic molecules in medicinal chemistry.

Basic Information

Product Name	6-Iodo-Uridine
CAS No.	105967-11-1
Molecular Formula	C9H11IN2O6
Molecular Weight	370.10 g/mol
Synonyms	6-Iodouridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione; 5-Iodo-1-β-D-ribofuranosyluracil; Uridine, 6-iodo-; 5-Iodouridine
EINECS	Contact for details

Quality Control

Our 6-Iodo-Uridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.