Description

9-(4-Hydroxy-2-(Hydroxymethyl)Butyl)Guanine is a high-purity guanine derivative, a key nucleobase analog used in advanced pharmaceutical and biochemical research. This compound is valued for its role as a critical intermediate in the synthesis of novel antiviral agents and nucleotide-based therapeutics. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing targeted treatments and diagnostic tools.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of antiviral drugs and nucleotide analogs.
• Biochemical Research: Used in studies involving DNA/RNA synthesis, enzyme inhibition, and cellular metabolism pathways.
• Antiviral Agent Development: Serves as a precursor in the research and production of compounds targeting viral polymerases.
• Life Science Reagents: Incorporated into high-purity reagents for molecular biology and diagnostic assay development.
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry and drug discovery projects.
• Nucleotide Chemistry: Fundamental for modifying nucleosides and exploring structure-activity relationships (SAR).

Basic Information

Product Name	9-(4-Hydroxy-2-(Hydroxymethyl)Butyl)Guanine
CAS No.	105868-85-7
Molecular Formula	C11H17N5O3
Molecular Weight	267.29 g/mol
Synonyms	9-[(4-Hydroxy-2-(hydroxymethyl)butyl]guanine; 2-Amino-9-[(4-hydroxy-2-(hydroxymethyl)butyl]-1,9-dihydro-6H-purin-6-one; H2G; (R)-9-(4-Hydroxy-2-(hydroxymethyl)butyl)guanine; Guanine, 9-[4-hydroxy-2-(hydroxymethyl)butyl]-; Acyclovir guanine analog; Nucleobase derivative; Bicyclic nucleoside analog
EINECS	Contact for details

Quality Control

Our 9-(4-Hydroxy-2-(Hydroxymethyl)Butyl)Guanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.