Description

2-Methylestra-4,9-Dien-3-One-17-Ol CAS NO 105802-53-7 is a high-purity synthetic steroid derivative, specifically a modified estratriene compound. This specialized intermediate is critical for pharmaceutical research and development, offering a precise molecular scaffold for creating novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on endocrinology, oncology, and metabolic disease treatment development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in studies investigating steroid hormone receptors, signaling pathways, and metabolic processes.
• Hormone Analog Development: Acts as a core structure for developing selective estrogen receptor modulators (SERMs) and other targeted endocrine therapies.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and pharmacological screening.
• Process Development: Used in scaling up synthetic routes for advanced steroid compounds under Good Manufacturing Practice (GMP) conditions.

Basic Information

Product Name	2-Methylestra-4,9-Dien-3-One-17-Ol
CAS No.	105802-53-7
Molecular Formula	C20H28O2
Molecular Weight	300.44 g/mol
Synonyms	17β-Hydroxy-2-methylestra-4,9-dien-3-one; 2-Methyl-19-nor-4,9-androstadiene-3,17-dione (reduced form); 2-Methylestra-4,9-diene-3,17-diol (ketone form); 2-Methyl-4,9-estradien-3-one-17β-ol; 2-Me-Estra-4,9-dien-3-one-17β-ol; 105802-53-7; 2-Methyl-19-norpregna-4,9-diene-3,20-dione derivative
EINECS	Contact for details

Quality Control

Our 2-Methylestra-4,9-Dien-3-One-17-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.