Description

Clitocine is a potent nucleoside antibiotic isolated from the mushroom *Clitocybe inversa*, known for its unique chemical structure and significant biological activity. This compound is of high interest in biochemical and pharmaceutical research due to its ability to inhibit adenosine kinase, a key enzyme in purine metabolism. It serves as a critical reference standard and research tool for scientists in the fields of oncology, immunology, and enzymology, supporting the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a selective and potent inhibitor of adenosine kinase (AK) in enzymatic assays and metabolic pathway studies.
• Pharmaceutical R&D: Serves as a reference standard and lead compound in the discovery and development of new anticancer and anti-inflammatory agents.
• Immunology Studies: Employed to investigate the role of adenosine signaling in immune cell regulation and inflammatory responses.
• Academic Research: A key tool for studying nucleoside metabolism, enzyme kinetics, and the biochemical mechanisms of natural product antibiotics.
• Standards & Calibration: Used as a high-purity analytical standard for quality control and method validation in laboratory testing.

Basic Information

Product Name	Clitocine
CAS No.	105798-74-1
Molecular Formula	C₁₁H₁₅N₅O₄
Molecular Weight	281.27 g/mol
Synonyms	Clitocine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-3,4-diol; 9-((2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-9H-purin-6-amine; Antibiotic LL-Z1272β; Adenosine Kinase Inhibitor
EINECS	Contact for details

Quality Control

Our Clitocine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, ensuring reliable performance as a biochemical tool.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.