Description

Sumarotene is a synthetic retinoid compound with significant research and development applications. This compound matters for its role as a selective agonist for retinoic acid receptors, which are critical targets in cellular differentiation and proliferation studies. It is primarily needed by pharmaceutical R&D teams and academic researchers focused on dermatology, oncology, and metabolic disease pathways. Sumarotene CAS NO 105687-93-2 represents a high-purity tool for advancing therapeutic innovation.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel retinoid-based therapeutics.
• Dermatology Studies: Investigation into mechanisms for treating skin conditions such as psoriasis, acne, and photoaging.
• Oncology Research: Exploration of its effects on cancer cell differentiation and apoptosis in various cancer models.
• Biochemical Assays: Used as a ligand in receptor binding studies to understand retinoic acid receptor (RAR) activity.
• Academic & Institutional Research: Serves as a critical reagent in university and government lab studies on gene expression and cell signaling.
• Preclinical Development: Evaluation of pharmacokinetics, efficacy, and safety in animal models for potential drug candidates.

Basic Information

Product Name	Sumarotene
CAS No.	105687-93-2
Molecular Formula	C24H28O3
Molecular Weight	364.48 g/mol
Synonyms	CD 271; CD-271; Ro 26-4457; Ro 26-4457; Ro-26-4457; 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid; 4-[1-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)vinyl]benzoic Acid
EINECS	Contact for details

Quality Control

Our Sumarotene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.