Description

Bicyclo[4.2.0]Octane-1-Carbonyl Chloride, 5-Oxo-, cis- (9Ci) is a high-purity, specialized organic building block characterized by its strained bicyclic framework and reactive acid chloride functionality. This compound is critical for advanced synthetic chemistry, enabling the precise construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, where its unique structure offers a strategic advantage for introducing specific stereochemistry and functional groups.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Used in constructing advanced herbicide and pesticide molecules that require specific, rigid three-dimensional shapes for target binding.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Academic & Contract Research: Employed in methodological studies and the total synthesis of complex natural products in university and CRO laboratories.
• Peptide Mimetic Chemistry: Facilitates the introduction of constrained, non-peptide scaffolds into molecules designed to mimic biological peptides.

Basic Information

Product Name	Bicyclo[4.2.0]Octane-1-Carbonyl Chloride, 5-Oxo-, cis- (9Ci)
CAS No.	105539-62-6
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	cis-5-Oxobicyclo[4.2.0]octane-1-carbonyl chloride; 1-Carboxy-5-oxobicyclo[4.2.0]octane-1-carbonyl chloride, cis-; Bicyclo[4.2.0]octane-1-carbonyl chloride, 5-oxo-, (1R,6S)-rel-; 5-Oxobicyclo[4.2.0]octane-1-carbonyl chloride; (1R,6S)-5-Oxobicyclo[4.2.0]octane-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[4.2.0]Octane-1-Carbonyl Chloride, 5-Oxo-, cis- (9Ci) is manufactured and tested under strict quality management protocols to ensure consistency and reliability for critical research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.