Description

Bromoacetyl-S-Pantetheine 11-Pivalate is a key synthetic intermediate in advanced organic and medicinal chemistry. This compound is valued for its role as a functionalized pantetheine derivative, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, enzyme inhibitors, and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel drug candidates, particularly enzyme inhibitors and targeted therapeutics.
• Bioconjugation & Probe Development: Used to create labeled or functionalized biomolecules for biochemical research and diagnostic applications.
• Enzyme Mechanism Studies: Serves as a substrate analog or inhibitor in studying the function of Coenzyme A-dependent enzymes.
• Peptide & Protein Modification: Enables site-specific alkylation or functionalization of peptides and proteins due to its reactive bromoacetyl group.
• Chemical Biology Research: Employed in the synthesis of activity-based probes (ABPs) to profile enzyme activities in complex biological systems.
• Academic & Industrial R&D: A versatile reagent for synthetic chemistry research in both university laboratories and corporate R&D departments.

Basic Information

Product Name	Bromoacetyl-S-Pantetheine 11-Pivalate
CAS No.	105514-56-5
Molecular Formula	C18H31BrN2O7S
Molecular Weight	475.42 g/mol
Synonyms	11-O-(2,2-Dimethylpropanoyl)-N-[2-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]ethyl]-2-[(2-bromoacetyl)sulfanyl]ethanimidate; S-(2-Bromoacetyl)-11-O-pivaloyl-pantetheine; Bromoacetylpantetheine pivalate; N-[2-[(2R)-2,4-Dihydroxy-3,3-dimethylbutanamido]ethyl]-2-[(2-bromoacetyl)thio]acetimidic Acid 2,2-Dimethylpropanoate; 11-Pivaloyl-S-bromoacetylpantetheine
EINECS	Contact for details

Quality Control

Our Bromoacetyl-S-Pantetheine 11-Pivalate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach ambient temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.