Description

Fosfomycin Sodim is the sodium salt form of the broad-spectrum antibiotic fosfomycin. This compound is valued for its unique mechanism of action, inhibiting bacterial cell wall synthesis at an early stage, which makes it effective against a range of Gram-positive and Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of injectable and oral antibiotic formulations. Its utility extends to research and development within the antimicrobial sector.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable and oral antibiotic medications.
• Urinary Tract Infection (UTI) Treatment: Formulated into specific drugs targeting uncomplicated UTIs.
• Combination Therapy: Used in synergistic antibiotic combinations to combat multi-drug resistant bacterial infections.
• Veterinary Medicine: Manufacture of antibacterial treatments for livestock and companion animals.
• Clinical Research: Serves as a reference standard and key material in antimicrobial susceptibility studies and new drug development.
• Hospital Compounding: Used in pharmacy compounding for specific patient needs where commercial formulations are unsuitable.

Basic Information

Product Name	Fosfomycin Sodim
CAS No.	105507-57-1
Molecular Formula	C3H5Na2O4P
Molecular Weight	182.02 g/mol
Synonyms	Fosfomycin Sodium; Sodium Fosfomycin; (2R,3S)-(3-Methyloxiran-2-yl)phosphonic Acid Disodium Salt; Fosfomycin Disodium; Phosphomycin Sodium; MK-0955; FOM-Na; Antibiotic MK-0955
EINECS	Contact for details

Quality Control

Our Fosfomycin Sodim is manufactured under cGMP (current Good Manufacturing Practice) guidelines to ensure the highest standards of purity and consistency. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent pharmacopeial specifications (e.g., USP, EP). A detailed Certificate of Analysis (COA) documenting identity, purity, residual solvents, and microbiological quality is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
pH (10% solution)	8.0 - 10.0
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 0.17 IU/mg (for injectable grade)
Microbial Enumeration	Complies with EP/USP <61> and <62>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.