Description

6-Amino-5-Azacytidine is a high-purity nucleoside analog with significant research and pharmaceutical development potential. This compound is valued for its role as a key intermediate and active pharmaceutical ingredient (API) in the synthesis of novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology, epigenetics, and antiviral drug discovery. Our supply ensures consistent quality and reliable availability for critical development workflows.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced nucleoside-based therapeutics.
• Oncology Research: Investigated for its potential epigenetic modulatory effects and anti-cancer activity in preclinical studies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.
• Antiviral Agent Development: Explored for incorporation into nucleotide analogs targeting viral polymerases.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Life Science Reagent: Utilized in cell culture and molecular biology experiments to study cellular differentiation and gene expression.

Basic Information

Product Name	6-Amino-5-Azacytidine
CAS No.	105331-00-8
Molecular Formula	C7H11N5O4
Molecular Weight	229.19 g/mol
Synonyms	5-Azacytidine, 6-Amino-; 6-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one; 6-Aza-2'-deoxycytidine (obsolete); 6-Azacytidine; NSC 135023; 1-(β-D-Ribofuranosyl)-6-amino-1,3,5-triazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Azacytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.