Description

4,7-Methanoindene-2-Carbonylchloride,3A,4,5,6,7,7A-Hexahydro-(6Ci) is a specialized bicyclic organic acid chloride intermediate with significant utility in advanced synthetic chemistry. Its unique bridged structure makes it a valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in fine chemical synthesis, where it serves as a key precursor for amide and ester formation, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with complex polycyclic or bridged-ring frameworks targeting central nervous system (CNS) or anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its reactive acid chloride group facilitates the creation of new amide-based active ingredients.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and coatings, imparting unique thermal and mechanical properties.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, or advanced composites due to its rigid, three-dimensional structure.
• Organic Synthesis Reagent: A versatile reagent for introducing the methanoindene carbonyl moiety into larger molecules via nucleophilic acyl substitution reactions with amines and alcohols.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	4,7-Methanoindene-2-Carbonylchloride,3A,4,5,6,7,7A-Hexahydro-(6Ci)
CAS No.	105041-53-0
Molecular Formula	C11H11ClO
Molecular Weight	194.66 g/mol
Synonyms	3a,4,5,6,7,7a-Hexahydro-4,7-methano-1H-indene-2-carbonyl chloride; Hexahydro-4,7-methanoinden-2-carbonyl chloride; 4,7-Methano-1H-indene-2-carbonyl chloride, hexahydro-; 2-Carbonylchloride-3a,4,5,6,7,7a-hexahydro-4,7-methanoindene; Bicyclo[2.2.1]hept-5-ene-2-carbonyl chloride, 3a,4,5,6,7,7a-hexahydro- (related); Norbornene-derived acid chloride
EINECS	Contact for details

Quality Control

Our production of 4,7-Methanoindene-2-Carbonylchloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements under cGMP or ISO 9001 guidelines as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.