Description

3'-o-(4-Benzoyl)Benzoylcytidine 5'-Triphosphate is a chemically modified nucleoside triphosphate analog designed for advanced biochemical research and development. This compound is a critical reagent for site-specific crosslinking and photoaffinity labeling studies, enabling precise investigation of nucleic acid-protein interactions. It is primarily utilized by research institutions and biotechnology companies specializing in molecular biology, structural biology, and the development of novel diagnostic assays.

Application

• Photoaffinity Labeling: A key reagent for crosslinking proteins to RNA or DNA sequences to map binding sites and study interaction dynamics.
• Structural Biology Studies: Used in X-ray crystallography and cryo-EM to trap and stabilize transient nucleic acid-protein complexes.
• Mechanistic Enzymology: Employed to probe the active sites and mechanisms of polymerases, helicases, and other nucleic acid-modifying enzymes.
• Diagnostic Probe Development: Serves as a foundational component in creating high-specificity probes for detecting target biomolecules.
• Next-Generation Sequencing (NGS) Research: Investigated for potential use in developing novel sequencing chemistries or covalent capture techniques.
• Drug Discovery Platforms: Utilized in target identification and validation stages for diseases involving RNA-protein complexes.

Basic Information

Product Name	3'-o-(4-Benzoyl)Benzoylcytidine 5'-Triphosphate
CAS No.	104960-26-1
Molecular Formula	C₂₇H₂₈N₃O₁₇P₃
Molecular Weight	783.44 g/mol
Synonyms	3'-O-[4-(Benzoyl)benzoyl]cytidine 5'-triphosphate; 3'-O-(4-Benzoylbenzoyl)-CTP; BzBz-CTP; 3'-O-(p-Benzoylbenzoyl)cytidine 5'-triphosphate; Cytidine 5'-(tetrahydrogen triphosphate), 3'-[4-(benzoyl)benzoate]; Photoactivatable CTP; CTP, 3'-O-(4-benzoylbenzoyl)-; 3'-O-(4-Benzoylbenzoyl)cytidine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our production of 3'-o-(4-Benzoyl)Benzoylcytidine 5'-Triphosphate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and functional integrity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (UV)	≥ 90%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in aqueous buffer, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.