Description

16-Iodo-11-Methoxyestradiol is a halogenated derivative of estradiol, a key steroid hormone. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a molecular probe or a synthetic intermediate in the creation of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in steroid chemistry, radiopharmaceutical development, and endocrine system studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel steroid-based drugs and therapeutic candidates.
• Biochemical Research: Used as a molecular probe to study estrogen receptor binding, function, and signaling pathways.
• Radiopharmaceutical Precursor: The iodine atom provides a potential site for radioiodination (e.g., I-125, I-131) to create tracers for diagnostic imaging or research.
• Reference Standard: Employed as an analytical standard in HPLC, LC-MS, or NMR for method development, validation, and quality control in laboratories.
• Organic Synthesis: Acts as a specialized intermediate for chemists exploring new reactions and modifications in steroid chemistry.

Basic Information

Product Name	16-Iodo-11-Methoxyestradiol
CAS No.	104820-74-8
Molecular Formula	C19H25IO3
Molecular Weight	452.31 g/mol
Synonyms	11-Methoxy-16-iodoestra-1,3,5(10)-triene-3,17β-diol; 16-Iodo-11-methoxy-estra-1,3,5(10)-triene-3,17β-diol; 11-Methoxy-16-iodoestradiol; Estra-1,3,5(10)-triene-3,17-diol, 16-iodo-11-methoxy-, (17β)-; 16-Iodo-11β-methoxyestradiol
EINECS	Contact for details

Quality Control

Our 16-Iodo-11-Methoxyestradiol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing at 2-8°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.