Description

2'-o-Monosuccinyladenosine 3':5'-Cyclic Monophosphate Tyrosyl Methyl Ester is a chemically modified cyclic nucleotide derivative, specifically engineered for advanced biochemical research and pharmaceutical development. This compound is critical for studying intracellular signaling pathways, particularly those mediated by cyclic AMP (cAMP), due to its enhanced membrane permeability and targeted delivery capabilities. It is primarily utilized by research institutions and pharmaceutical companies engaged in signal transduction research, enzyme studies, and the development of novel therapeutic agents targeting metabolic and neurological disorders.

Application

• Biochemical Research: As a key tool compound for investigating cAMP-dependent protein kinase (PKA) activation and other second messenger systems.
• Pharmaceutical R&D: Serving as a precursor or intermediate in the synthesis of novel drug candidates targeting metabolic diseases.
• Cell Signaling Studies: Used to modulate intracellular cAMP levels in cell culture models to study cellular responses and gene expression.
• Enzyme Substrate: Acting as a specific substrate for studies involving phosphodiesterases (PDEs) and other nucleotide-metabolizing enzymes.
• Probe Development: Utilized in the creation of fluorescent or affinity-labeled probes for visualizing cAMP dynamics in live cells.
• Metabolic Pathway Analysis: Applied in research focused on energy metabolism, hormone action, and neuronal function.

Basic Information

Product Name	2'-o-Monosuccinyladenosine 3':5'-Cyclic Monophosphate Tyrosyl Methyl Ester
CAS No.	104809-08-7
Molecular Formula	C25H27N7O11P
Molecular Weight	656.50 g/mol
Synonyms	2'-O-Succinyl-cAMP Tyrosyl Methyl Ester; 2'-O-Monosuccinyl-cAMP-Tyr-OMe; N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate tyrosyl methyl ester analog; cAMP derivative, succinyl-tyrosine methyl ester; Adenosine 3',5'-cyclic monophosphate, 2'-O-monosuccinyl, tyrosyl methyl ester; 8-(4-Chlorophenylthio)-2'-O-monosuccinyladenosine-3',5'-cyclic monophosphate tyrosyl methyl ester (related analog); SC-AMP-Tyr-OMe
EINECS	Contact for details

Quality Control

Our 2'-o-Monosuccinyladenosine 3':5'-Cyclic Monophosphate Tyrosyl Methyl Ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and storage under an inert atmosphere to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.