Description

Cholest-5-Ene-3,7,22-Triol is a high-purity sterol derivative, a key intermediate in the synthesis of complex bioactive molecules. Its precise chemical structure makes it an essential building block for research and development in advanced pharmaceutical and fine chemical applications. This compound is particularly valuable for scientists and manufacturers working on steroid-based drug discovery, vitamin D analogs, and other specialized biochemical pathways.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies, enzyme inhibition assays, and receptor binding research.
• Fine Chemical Synthesis: Serves as a chiral building block for the production of complex, high-value specialty chemicals and advanced materials.
• Vitamin D Analog Development: A key precursor in the research and development of vitamin D metabolites and related analogs with potential therapeutic applications.
• Academic & Industrial R&D: Employed in laboratories for method development, process chemistry optimization, and exploratory synthesis projects.

Basic Information

Product Name	Cholest-5-Ene-3,7,22-Triol
CAS No.	104786-66-5
Molecular Formula	C₂₇H₄₆O₃
Molecular Weight	418.66 g/mol
Synonyms	3β,7α,22-Trihydroxycholest-5-ene; (3β,7α,22R)-Cholest-5-ene-3,7,22-triol; 22R-Hydroxycholesterol (7α-hydroxy derivative); 7α,22-Dihydroxycholesterol; Cholest-5-ene-3β,7α,22(R)-triol; 5-Cholestene-3β,7α,22-triol
EINECS	Contact for details

Quality Control

Our Cholest-5-Ene-3,7,22-Triol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.