Description

7-(2,3-Dihydroxypropane)Deoxyguanosine is a modified nucleoside derivative, specifically a deoxyguanosine analog with a 2,3-dihydroxypropane side chain. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of complex nucleotide analogs and oligonucleotides. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic reagent production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleotide prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to DNA repair and replication mechanisms.
• Oligonucleotide Synthesis: Serves as a modified monomer for creating specialized DNA probes and primers with altered properties.
• Diagnostic Development: Employed in the manufacture of labeled nucleotides for diagnostic assays and sequencing applications.
• Reference Standard: Acts as a high-purity analytical standard for quality control in nucleotide manufacturing.

Basic Information

Product Name	7-(2,3-Dihydroxypropane)Deoxyguanosine
CAS No.	104764-31-0
Molecular Formula	C13H19N5O6
Molecular Weight	341.32 g/mol
Synonyms	7-(2,3-Dihydroxypropyl)deoxyguanosine; 7-(2,3-Dihydroxypropyl)-2'-deoxyguanosine; 7-HP-dG; 7-(2-Hydroxy-3-hydroxypropyl)-2'-deoxyguanosine; N7-(2,3-Dihydroxypropyl)-2'-deoxyguanosine; 2'-Deoxy-7-(2,3-dihydroxypropyl)guanosine; dG-7-HP
EINECS	Contact for details

Quality Control

Our 7-(2,3-Dihydroxypropane)Deoxyguanosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to ensure it meets the stringent requirements for research and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.