Description

2-Buten-1-Ol, 4-(6-Amino-9H-Purin-9-Yl)-, (E)- is a high-purity nucleoside analogue building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of modified nucleosides and nucleotides, which are essential in the development of antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the creation of novel active pharmaceutical ingredients (APIs) and prodrugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used in studies exploring enzyme inhibition, nucleotide metabolism, and the mechanism of action of therapeutic compounds.
• Prodrug Development: Serves as a precursor in the design of prodrugs to enhance the bioavailability and targeting of nucleotide analogues.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical entities.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	2-Buten-1-Ol, 4-(6-Amino-9H-Purin-9-Yl)-, (E)-
CAS No.	104715-57-3
Molecular Formula	C9H11N5O
Molecular Weight	205.22 g/mol
Synonyms	(E)-4-(6-Amino-9H-purin-9-yl)-2-buten-1-ol; 9-[(1E)-4-Hydroxy-2-buten-1-yl]adenine; trans-4-(6-Aminopurin-9-yl)but-2-en-1-ol; 4-(6-Amino-9H-purin-9-yl)-2-buten-1-ol, (E)-; Adenine butenol derivative; Nucleoside analogue intermediate
EINECS	Contact for details

Quality Control

Our 2-Buten-1-Ol, 4-(6-Amino-9H-Purin-9-Yl)-, (E)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability, consistency, and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.