Description

Barnidipine is a potent and selective dihydropyridine calcium channel blocker used primarily in pharmaceutical research and development. This compound is crucial for studying cardiovascular pharmacology, particularly in the context of hypertension and angina. It is a key intermediate and reference standard for researchers and manufacturers in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Active Ingredient (API): Serves as the core active component in the formulation of antihypertensive medications.
• Research & Development: Used as a reference standard in pharmacological studies to investigate calcium channel modulation and cardiovascular effects.
• Process Development: Acts as a critical intermediate in the synthesis and scale-up of advanced pharmaceutical compounds.
• Analytical Testing: Employed as a high-purity standard in quality control laboratories for method development and validation (HPLC, GC, etc.).
• Preclinical Studies: Utilized in animal models to evaluate the efficacy, pharmacokinetics, and safety profile of new cardiovascular drug candidates.

Basic Information

Item	Details
Product Name	Barnidipine
CAS No.	104713-75-9
Molecular Formula	C27H29N3O6
Molecular Weight	491.54 g/mol
Synonyms	Barnidipine Hydrochloride; Mepirodipine; YM-730; (±)-Barnidipine; (RS)-Barnidipine; 3-(1-Benzyl-3-piperidyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; Hypoca; Cyress
EINECS	Contact for details

Quality Control

Our Barnidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.