Description

3,3'-Dithiobis(2'-o-6-(Propionylamino)Hexanoyl)Adenosine 5'-Triphosphate is a specialized, chemically modified nucleotide analog designed for advanced biochemical research and diagnostic applications. This compound matters as a critical reagent for studying enzyme kinetics, nucleic acid metabolism, and for developing sensitive detection assays due to its unique disulfide-linked, acylated structure. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on molecular biology, enzymology, and high-throughput screening platforms.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly for ATP-dependent enzymes and kinases, to investigate reaction mechanisms and kinetics.
• Diagnostic Assay Development: Serves as a key component in the formulation of chemiluminescent or colorimetric detection kits for clinical diagnostics and life science research.
• Probe Synthesis: Acts as a building block for synthesizing labeled nucleotide probes for hybridization and detection in molecular biology techniques.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) assays to identify and characterize potential drug candidates that modulate nucleotide-binding proteins.
• Cross-linking Studies: Utilized in structural biology research due to its disulfide bridge, which can be used for reversible cross-linking or affinity labeling of proteins.
• Metabolic Pathway Analysis: Applied in tracing and analyzing specific metabolic pathways involving nucleotide derivatives in cellular systems.

Basic Information

Item	Detail
Product Name	3,3'-Dithiobis(2'-o-6-(Propionylamino)Hexanoyl)Adenosine 5'-Triphosphate
CAS No.	104693-48-3
Molecular Formula	C34H50N10O23P6S2
Molecular Weight	1244.86 g/mol
Synonyms	Disulfide-linked Acylated ATP; 3,3'-Dithiobis[2'-O-[6-(propionylamino)hexanoyl]adenosine 5'-triphosphate]; Modified ATP disulfide analog; Acyl-ATP disulfide; ATP-SS-(Propionyl-Hexanoyl); Nucleotide cross-linking reagent; Bifunctional ATP derivative; CAS 104693-48-3
EINECS	Contact for details

Quality Control

Our 3,3'-Dithiobis(2'-o-6-(Propionylamino)Hexanoyl)Adenosine 5'-Triphosphate is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic identification (NMR, MS), to ensure consistency and meet the exacting standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data and specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.