Description

N4-Benzoyl-5-Methyldeoxycytidine CAS NO 104579-02-4 is a chemically modified nucleoside derivative, specifically a protected form of deoxycytidine. This compound is of significant value as a key synthetic intermediate and building block in advanced organic and medicinal chemistry. It is primarily required by researchers and manufacturers in the pharmaceutical and biotechnology sectors for applications such as oligonucleotide synthesis and the development of novel therapeutic agents.

Application

• Oligonucleotide Synthesis: Serves as a protected phosphoramidite monomer for the solid-phase synthesis of DNA and RNA strands, particularly those containing modified bases.
• Antiviral Drug Research: Used as a critical intermediate in the development and study of nucleoside analogue prodrugs targeting viral polymerases.
• Anticancer Agent Development: Employed in the synthesis of novel chemotherapeutic compounds that incorporate modified cytidine structures to disrupt DNA replication in cancer cells.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to understand the mechanisms of nucleoside-metabolizing enzymes.
• Prodrug Synthesis: Utilized in creating prodrug forms of bioactive nucleosides to enhance their stability, bioavailability, and targeted delivery.
• Labeled Compound Preparation: A precursor for synthesizing isotopically labeled (e.g., 13C, 15N) nucleosides for use in metabolic tracing and NMR studies.

Basic Information

Product Name	N4-Benzoyl-5-Methyldeoxycytidine
CAS No.	104579-02-4
Molecular Formula	C17H19N3O5
Molecular Weight	345.35 g/mol
Synonyms	5-Methyl-2'-deoxycytidine N4-benzoate; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-4-(benzoylamino)-2(1H)-pyrimidinone; N4-Benzoyl-5-methyl-2'-deoxycytidine; 4-N-Benzoyl-5-methyldeoxycytidine; Bz-5-Me-dC; N4-Bz-5-MedC; 5-Methyldeoxycytidine N4-benzoate
EINECS	Contact for details

Quality Control

Our N4-Benzoyl-5-Methyldeoxycytidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and pharmaceutical synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.