Description

1,3,4-Thiadiazole-2-Carbonyl Chloride, 97% is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecules with the 1,3,4-thiadiazole core, a privileged scaffold known for imparting significant biological activity. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those targeting infectious diseases, cancer, and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole moiety.
• Material Science Research: Serves as a precursor for creating functional polymers, ligands for metal complexes, and other specialty chemicals.
• Peptide Mimetics & Bioconjugation: The reactive acid chloride group enables efficient coupling reactions for creating peptide analogs or labeling biomolecules.
• Academic & R&D Laboratories: Fundamental reagent for methodological studies and exploring new synthetic routes in heterocyclic chemistry.

Basic Information

Product Name	1,3,4-Thiadiazole-2-Carbonyl Chloride, 97%
CAS No.	104473-08-7
Molecular Formula	C3HN2OSCl
Molecular Weight	148.57 g/mol
Synonyms	1,3,4-Thiadiazole-2-carbonyl chloride; 1,3,4-Thiadiazole-2-carboxylic acid chloride; 2-Carbonyl chloride-1,3,4-thiadiazole; Thiadiazole-2-carbonyl chloride; 1,3,4-Thiadiazolecarbonyl chloride; 2-(Chlorocarbonyl)-1,3,4-thiadiazole; 1,3,4-Thiadiazol-2-yl carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1,3,4-Thiadiazole-2-Carbonyl Chloride, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the declared specification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended storage temperature: 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.