Description

4-Bromo-2-(Trifluoromethyl)Benzoyl Chloride is a high-value aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents, enables precise molecular modifications essential for developing compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring bromo- and trifluoromethyl-phenyl motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the halogenated benzoyl group is integral to biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores in electronic and display materials.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce specific functional groups into polymer chains, enhancing material properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science.

Basic Information

Item	Details
Product Name	4-Bromo-2-(Trifluoromethyl)Benzoyl Chloride
CAS No.	104356-17-4
Molecular Formula	C8H3BrClF3O
Molecular Weight	287.46 g/mol
Synonyms	4-Bromo-2-(trifluoromethyl)benzoyl chloride; 2-Trifluoromethyl-4-bromobenzoyl chloride; 4-Bromo-alpha,alpha,α-trifluoro-o-toluoyl chloride; Benzoyl chloride, 4-bromo-2-(trifluoromethyl)-; 4-Bromo-2-trifluoromethylbenzoyl chloride; o-Trifluoromethyl-p-bromobenzoyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(Trifluoromethyl)Benzoyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.