Description

3-Cyclohexene-1-Carboxylic Acid, 6-(Chlorocarbonyl)-, Methyl Ester, (1R-Trans)- (9Ci) is a high-purity chiral building block and key synthetic intermediate. Its value lies in its functionalized cyclohexene core and reactive acid chloride group, enabling precise stereochemistry in complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Fine Chemical Production: Serves as a versatile precursor for creating complex, high-value specialty chemicals and flavors/fragrances.
• Academic & Contract Research: Employed in research laboratories for methodological development in asymmetric synthesis and organocatalysis.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	3-Cyclohexene-1-Carboxylic Acid, 6-(Chlorocarbonyl)-, Methyl Ester, (1R-Trans)- (9Ci)
CAS No.	104265-87-4
Molecular Formula	C9H11ClO3
Molecular Weight	202.63 g/mol
Synonyms	(1R,6R)-6-(Chlorocarbonyl)-3-cyclohexene-1-carboxylic acid methyl ester; Methyl (1R,6R)-6-(chlorocarbonyl)cyclohex-3-ene-1-carboxylate; trans-6-(Chlorocarbonyl)-3-cyclohexene-1-carboxylic acid methyl ester; (1R-trans)-6-(Chlorocarbonyl)-3-cyclohexenecarboxylic Acid Methyl Ester; (1R,6R)-6-(Methoxycarbonyl)cyclohex-3-ene-1-carbonyl chloride; A chiral cyclohexene acid chloride ester
EINECS	Contact for details

Quality Control

Our production of 3-Cyclohexene-1-Carboxylic Acid, 6-(Chlorocarbonyl)-, Methyl Ester, (1R-Trans)- (9Ci) adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like chiral HPLC, GC, and NMR to ensure high enantiomeric purity and chemical identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency, meeting the rigorous demands of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.